Can Raman Spectroscopy be used to determine the concentration of a specific substance in a mixture or solution?

Raman spectroscopy is widely used to determine the presence of a substance in a mixture or solution.  For quantitative measurement, the intensity of the Raman signal/peaks can be used to infer the concentration, however, a calibration process is normally needed to determine the concentration level and the corresponding Raman signals/peaks, with highly control environmental parameters to ensure accuracy.